FEASIBILITY AND SAFETY OF RESEARCH SIGMOID COLON BIOPSY IN A COHORT OF THAI MEN WHO HAVE SEX WITH MEN WITH ACUTE HIV-1

Feasibility and safety of research sigmoid colon biopsy in a cohort of Thai men who have sex with men with acute HIV-1

Background: The gut-associated lymphoid tissue (GALT) is a major reservoir of HIV-1 established early in acute HIV-1 infection (AHI).Sampling tissue from GALT can provide information about viral reservoirs and immune responses but may be complicated during AHI for reasons such as high viral replication, CD4 T cell depletion and immune activation.Ri

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